TAC1 Gene Products Regulate Pituitary Hormone Secretion and Gene Expression in Prepubertal Grass Carp Pituitary Cells
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چکیده
منابع مشابه
Signaling mechanisms for alpha2-adrenergic inhibition of PACAP-induced growth hormone secretion and gene expression grass carp pituitary cells.
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a potent growth hormone (GH)-releasing factor in lower vertebrates. However, its functional interactions with other GH regulators have not been fully characterized. In fish models, norepinephrine (NE) inhibits GH release at the pituitary cell level, but its effects on GH synthesis have yet to be determined. We examined adrenergic inh...
متن کاملSignaling mechanisms for 2-adrenergic inhibition of PACAP-induced growth hormone secretion and gene expression grass carp pituitary cells
Wang X, Chu MM, Wong AO. Signaling mechanisms for 2-adrenergic inhibition of PACAP-induced growth hormone secretion and gene expression grass carp pituitary cells. Am J Physiol Endocrinol Metab 292: E1750 –E1762, 2007. First published February 20, 2007; doi:10.1152/ajpendo.00001.2007.—Pituitary adenylate cyclase-activating polypeptide (PACAP) is a potent growth hormone (GH)-releasing factor in ...
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Gonadotrophin regulation by activin/follistatin system is well-documented, but the corresponding effect on growth hormone (GH) has not been fully characterized and with little information available in lower vertebrates, especially in fish models. In grass carp, local interactions of GH and luteinizing hormone (LH) can induce GH release and gene expression at pituitary level via autocrine/paracr...
متن کاملPulsatile patterns of pituitary hormone gene expression change during development.
Important questions in biology have emerged recently concerning the timing of transcription in living cells. Studies on clonal cell lines have shown that transcription is often pulsatile and stochastic, with implications for cellular differentiation. Currently, information regarding transcriptional activity at cellular resolution within a physiological context remains limited. To investigate si...
متن کاملGrass carp somatolactin: I. Evidence for PACAP induction of somatolactin- and - gene expression via activation of pituitary PAC-I receptors
Jiang Q, Ko WK, Lerner EA, Chan KM, Wong AO. Grass carp somatolactin: I. Evidence for PACAP induction of somatolactinand gene expression via activation of pituitary PAC-I receptors. Am J Physiol Endocrinol Metab 295: E463–E476, 2008. First published June 3, 2008; doi:10.1152/ajpendo.90385.2008.—Somatolactin (SL), the latest member of the growth hormone/prolactin family, is a novel pituitary hor...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2017
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2016-1740